drugset / Trial / NCT05825365

Selumetinib in Chinese Paediatric With Post-operative NF1-PNs, PhaseⅡ, Double-Blinded, Placebo-Controlled Study

NCT05825365

Phase 2 Withdrawn AstraZeneca
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a phase II, multicenter, randomised, parallel, double-blind, placebo-controlled study assessing the efficacy and safety of the MEKi selumetinib compared with placebo in Chinese paediatric participants with post-operative NF1-associated PNs.

Timeline

Start
2023-08-31
Primary completion
2026-06-30
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Selumetinib Small molecule 25 mg/m2 Oral