drugset / Trial / NCT05828225

Evaluate the Safety and Efficacy of CAR-T Cells in the Treatment of Refractory Myasthenia Gravis

NCT05828225

Phase 1 Unknown 9 enrolled Zhejiang University
NaSingle-groupOpen-labelTreatment

Summary

This is a single-arm, open-label, single-center, phase I study. The primary objective is to evaluate the safety of CD19 CAR-T therapy for patients with refractory myasthenia gravis, and to evaluate the pharmacokinetics of CD19 CAR-T in patients.

Timeline

Start
2023-04-30
Primary completion
2026-04-20
Completion
2026-04-20

Drugs

EvaluationDrugModalityDoseRoute
Subject CD19 CAR-T cells Cell therapy

Indications