drugset / Trial / NCT05831995
Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.
Non-randomizedSequentialOpen-labelTreatment
Summary
This is a Phase 1, First-in-Human (FIH), open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of ABM-168 in adult patients with RAS or RAF or NF-1 mutated advanced solid tumors as ABM-168 may have a significant effect in inhibiting cell growth.
Timeline
- Start
- 2023-03-30
- Primary completion
- 2024-06-30
- Completion
- 2024-06-30
Outcome
Outcome not reported
Stopped (Business): “Due to development strategy change.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ABM-168 | Unknown | 0.5 mg | Oral |
| Subject | ABM-168 | Unknown | 2 mg | Oral |
| Subject | ABM-168 | Unknown | 6 mg | Oral |