drugset / Trial / NCT05833971

Cadonilimab in Combination With Chemotherapy for Locally Advaced Esophageal Squamous Cell Carcinoma

NCT05833971 ↗

Phase 2 Unknown 43 enrolled Guangzhou Institute of Respiratory Disease
NaSingle-groupOpen-labelTreatment

Summary

This is a single-arm, multicenter, exploratory study to evaluate the efficacy and safety of AK104 in combination with cisplatin and paclitaxel in the treatment of resectable locally advanced esophageal squamous carcinoma.

Timeline

Start
2023-05-01
Primary completion
2024-06-01
Completion
2026-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Albumin paclitaxel Unknown 260 mg/m2 Intravenous
Subject Cadonilimab Monoclonal antibody 10 mg/kg Intravenous
Subject Cisplatin Other / unclassified 60 mg/m2 Intravenous
Subject Cisplatin Other / unclassified 75 mg/m2 Intravenous