drugset / Trial / NCT05846880

VitD3 Supplementation in Patients With Multiple Myeloma

NCT05846880

Phase 0 Recruiting 100 enrolled Amany Keruakous, MD, MS.
RandomizedParallel-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to evaluate post-transplant immune reconstitution and lymphocyte recovery as well as the 3-year progression-free survival of patients with multiple myeloma in two treatment arms. One arm will receive Maintenance Vitamin D and the other arm will receive no maintenance Vitamin D prior to ASCT. Post ASCT arm 1 will have lenalidomide and maintenance VitD, and arm 2 will receive lenalidomide and no maintenance VitD. This clinical trial will also evaluate the overall response rate and survival for both treatment arms.

Timeline

Start
2024-12-01
Primary completion
2028-05
Completion
2028-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Cholecalciferol Other / unclassified 50000 iu
Background Lenalidomide Other / unclassified 15 mg Oral

Indications