drugset / Trial / NCT05850832
Efficacy of Esmolol Versus Magnesium Sulphate on Quality of Recovery in Patients Undergoing Laparoscopic Cholecystectomy: Randomized Controlled Study
RandomizedParallel-groupDouble-blindTreatment
Summary
sixty patients, of both sexes, of ASA I or II planned for ambulatory laparoscopic cholecystectomy under general anaesthesia were engaged into 2 groups. Esmolol group were given 1 mg/kg loading dose followed by 30 μg/kg/min throughout the surgery, whereas magnesium sulphate (MgSo4) group were given loading dose 40 mg/kg over 15 mins then maintenance dose 15 mg/kg/h till end of surgery. General anaesthesia was standardized and postoperative analgesia included fentanyl. Variables denoting immediate recovery from anaesthesia, pain score and time of stay in PACU were recorded. White-Song score ≥ 12 along with pain score \< 4 were the cut off levels for patients' discharge from PACU.
Timeline
- Start
- 2022-10-05
- Primary completion
- 2023-01-05
- Completion
- 2023-04-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Esmolol | Other / unclassified | 30 ug/kg | — |
| Comparator | Magnesium Sulfate | Other / unclassified | 15 mg/kg | — |
Indications
No indication recorded.