the Safety and Efficacy Evaluation of HGI-002 Injection in Patients With Transfusion-Dependent α-Thalassemia

Summary

This is an open label study to evaluate the safety and efficacy of α-globin Restored Autologous Hematopoietic Stem Cells in α-Thalassemia Major Patients

Timeline

Start

2022-10-08

Primary completion

2026-12-30

Completion

2026-12-30

Publications

• Yin X, Qian L, Dong G, Chen Y, Zhou Y, Yang B, Liao G, Sun H, Guo H, Zeng X, Zou H, Ye T, He J, Yao W, Ouyang W, Zhang X, Liu C. Successful gene therapy for transfusion-dependent alpha-thalassemia: a case report. Blood Adv. 2026 May 27:bloodadvances.2025019280. doi: 10.1182/bloodadvances.2025019280. Online ahead of print.

Drugs

Indications