drugset / Trial / NCT05853367

Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)

NCT05853367

Phase 1 Active not recruiting 95 enrolled Merck Sharp & Dohme LLC
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the efficacy, safety, and tolerability of MK-0472 administered as monotherapy and in combination with pembrolizumab (MK-3475) or MK-1084 in participants with histologically or cytologically confirmed diagnosis of advanced/metastatic solid tumors.

Timeline

Start
2023-07-06
Primary completion
2028-06-24
Completion
2028-06-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Calderasib Unknown Oral
Subject MK-0472 Unknown Oral
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous