drugset / Trial / NCT05853471

[18F]MC225-PET in Neurodegenerative Disease

NCT05853471 ↗

Phase 1/2 Unknown 30 enrolled University Medical Center Groningen
Non-randomizedParallel-groupOpen-labelDiagnostic

Summary

P-glycoprotein, an efflux transporter at the blood-brain barrier plays an important role in de development of neurodegenerative disease. A novel PET tracer (\[18F\]MC225) was developed to measure the function of P-glycoprotein and was tested with succes in healthy volunteers. This study aims to evaluate \[18F\]MC225 in neurodegenerative disease.

Timeline

Start
2022-02-01
Primary completion
2024-01-01
Completion
2024-01-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator [18F]MC225 Diagnostic / imaging agent — —