drugset / Trial / NCT05855330
Arginine Replacement Therapy in COVID-19
RandomizedParallel-groupOpen-labelTreatment
Summary
This study aims to investigate if receiving doses of arginine (a protein in the body) will improve mitochondria function in children with COVID-19. The study will be performed at the Children's Healthcare of Atlanta, Arthur M. Blank Hospital. Patients will be randomized to receive one of three doses of arginine three times a day for five days or at discharge whichever comes first.
Timeline
- Start
- 2024-01-08
- Primary completion
- 2028-06
- Completion
- 2028-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | L-arginine | Small molecule | 25 mg/kg | Intravenous |
| Comparator | L-arginine | Small molecule | 100 mg/kg | Intravenous |