Comparing the Efficacy of Mulberry Twig Alkaloid Tablet and Canagliflozin in Patients With Type 2 Diabetes

Phase 4 Unknown 60 enrolled Nanjing First Hospital, Nanjing Medical University

RandomizedParallel-groupSingle-blindTreatment

Summary

The aim of the study is to investigate the efficacy and safety of Mulberry Twig (Ramulus Mori, Sangzhi) Alkaloid Tablet and Canagliflozin for 12 weeks in individuals with type 2 diabetes mellitus

Timeline

Start: 2022-03-15
Primary completion: 2023-05-31
Completion: 2023-12-31

Publications

Li H, Tao S, Zhou X, Yan R, Yu B, Luo Y, Zhang P, Kong X, Ma J. Effects of mulberry twig alkaloids and canagliflozin in inadequately controlled type 2 diabetes: a randomized controlled study based on flash glucose monitoring. Sci Rep. 2026 Apr 21;16(1):18502. doi: 10.1038/s41598-026-48843-2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	CANAGLIFLOZIN ANHYDROUS	Small molecule	100 mg	Oral
Subject	Mulberry Twig (Ramulus Mori, Sangzhi) Alkaloid Tablet 50mg po tid	Unknown	50 mg	Oral

Comparing the Efficacy of Mulberry Twig Alkaloid Tablet and Canagliflozin in Patients With Type 2 Diabetes

Summary

Timeline

Publications

Drugs

Indications