drugset / Trial / NCT05856760

A Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in Participants With IgAN

NCT05856760

Phase 2 Completed 48 enrolled Travere Therapeutics, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This was a 28-week, open-label, multicenter, single-group Phase 2 exploratory study to determine the safety and effect of sparsentan in participants with IgAN who are at risk of disease progression to kidney failure despite being on both stable RAASi and SGLT2 inhibitor treatment for at least 12 weeks prior to study entry

Timeline

Start
2023-05-19
Primary completion
2024-10-14
Completion
2024-10-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Sparsentan Small molecule 400 mg Oral