drugset / Trial / NCT05857410

Scheme of Limb Warming Blanket Combined With Dexmedetomidine

NCT05857410

Completed 160 enrolled Jincheng General Hospital
RandomizedFactorialSingle-blindPrevention

Summary

Objective: To observe the clinical effect of lower limb warming blanket combined with dexmedetomidine (DEX) in preventing postoperative delirium (POD) and chills in elderly patients undergoing spinal surgery. Methods: A total of 160 elderly patients undergoing posterior spinal surgery under general anesthesia were selected and divided into control group (group N), heating group (group T), DEX group (group D) and heating combined with DEX group (group TD) according to the random number table method, 40 cases in each group. T group and TD group routine insulation and lower limb heating blanket. DEX was injected in group D and group TD. The dosage of anesthetics, the changes of body temperature and heart rate at different time points during operation, and the occurrence of postoperative chills and POD were compared among the groups.

Timeline

Start
2019-01-01
Primary completion
2022-12-30
Completion
2023-01-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmetomidine Unknown 0.4 ug/kg

Indications