drugset / Trial / NCT05861310
Effectivity and Safety of Metronidazole 1% Cream in Rosacea Therapy
Phase 1
Unknown
48 enrolled
Indonesia University
Science and Technology Park, Center of Innovation Technologies for Human Health · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
Rosacea is a chronic inflammatory disease of the central facial region, which can also occur in the neck and chest regions. Microbes that play a role in rosacea are Demodex folliculorum and Helicobactor pylori. On the skin with rosacea have decreased skin barrier function. This clinical study will compare the effectiveness and safety of metronidazole 1% cream as the main therapy in rosacea patients. Participants who will become research subjects are women and men aged 18-60 years who meet the inclusion criteria. Research subjects were divided into 2 groups. The control group will use placebo cream (without the drug substance) and the comparison group will use metronidazole 1% cream.
Timeline
- Start
- 2023-05
- Primary completion
- 2023-07
- Completion
- 2023-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metronidazole | Small molecule | 1 % | Topical |