drugset / Trial / NCT05866172
HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC
RandomizedParallel-groupTriple-blindTreatment
Summary
Zoledronic acid was initially used for bone metastases in various malignancies. However, it is unknown whether hepatic arterial infusion chemotherapy combined with zoledronic acid can improve overall survival of unresectable hepatocellular carcinoma.
Timeline
- Start
- 2023-05-10
- Primary completion
- 2024-12-01
- Completion
- 2025-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Zoledronic acid | Other / unclassified | 4 mg | Intravenous |