drugset / Trial / NCT05866172

HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC

NCT05866172

Phase 3 Unknown 264 enrolled Sun Yat-sen University
RandomizedParallel-groupTriple-blindTreatment

Summary

Zoledronic acid was initially used for bone metastases in various malignancies. However, it is unknown whether hepatic arterial infusion chemotherapy combined with zoledronic acid can improve overall survival of unresectable hepatocellular carcinoma.

Timeline

Start
2023-05-10
Primary completion
2024-12-01
Completion
2025-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Zoledronic acid Other / unclassified 4 mg Intravenous