drugset / Trial / NCT05867654
Efficacy of Oral vs IV Antibiotics in the Treatment of Orofacial Osteomyelitis
NaSingle-groupOpen-labelTreatment
Summary
The goal of this clinical trial is compare the efficacy of oral and IV antibiotics in the treatment of orofacial osteomyelitis. The main question it aims to answer is: Are oral antibiotics as effective as IV antibiotics in the treatment of orofacial osteomyelitis. Participants, once diagnosed with osteomyelitis, will be started on oral antibiotics for their treatment. Participants will follow up with oral and maxillofacial surgery clinic accordingly and their progression and compliance will be monitored.
Timeline
- Start
- 2024-07-31
- Primary completion
- 2025-11
- Completion
- 2025-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amoxicillin | Other / unclassified | 875 mg | Oral |
| Subject | Clavulanate | Unknown | 125 mg | Oral |
| Subject | Clindamycin | Unknown | 300 mg | Oral |
| Subject | Levofloxacin | Small molecule | 750 mg | Oral |