drugset / Trial / NCT05868083

The Safety and Efficacy of SNC-109 CAR-T Cells Therapy the Recurrent Glioblastoma

NCT05868083 ↗

NaSingle-groupOpen-labelTreatment

Summary

This is a single arm clinical study to estimate the safety, tolerability and pharmacokinetic (PK) characteristics of Chimeric Antigen Receptor-modified T cells (CAR-T) SNC-109 in patients with recurrent glioblastoma (r-GBM) and preliminarily evaluate the effectiveness, the immunogenicity of the product, as well as their correlation between the changes of cytokines from baseline level after cellular infusion.

Timeline

Start
2022-06-24
Primary completion
2024-05
Completion
2024-08

Drugs

EvaluationDrugModalityDoseRoute
Subject SNC-109 CAR-T Cells Cell therapy 20000 cells —

Indications