drugset / Trial / NCT05868083
The Safety and Efficacy of SNC-109 CAR-T Cells Therapy the Recurrent Glioblastoma
Phase 1
Unknown
16 enrolled
Shanghai Simnova Biotechnology Co.,Ltd.
Chinese PLA General Hospital · collab
NaSingle-groupOpen-labelTreatment
Summary
This is a single arm clinical study to estimate the safety, tolerability and pharmacokinetic (PK) characteristics of Chimeric Antigen Receptor-modified T cells (CAR-T) SNC-109 in patients with recurrent glioblastoma (r-GBM) and preliminarily evaluate the effectiveness, the immunogenicity of the product, as well as their correlation between the changes of cytokines from baseline level after cellular infusion.
Timeline
- Start
- 2022-06-24
- Primary completion
- 2024-05
- Completion
- 2024-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | SNC-109 CAR-T Cells | Cell therapy | 20000 cells | — |