drugset / Trial / NCT05872659
Mesenchymal Stem Cells for Immune Non-responder Patients With HIV Infection
Phase 0
Unknown
20 enrolled
Shandong Qilu Cell Therapy Engineering Technology Co., Ltd
Shandong Public Health Clinical Center · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The goal of this clinical trial is to explore the effect of mesenchymal stem cell therapy on immune non-responder patients. The main questions it aims to answer are: 1. Efficacy of human umbilical cord mesenchymal stem cells combined with antiviral therapy in the treatment of AIDS patients with immune non-response. 2. Safety of human umbilical cord mesenchymal stem cells combined with antiviral therapy in AIDS patients with immune non-response. Participants will receive CD4,CD4/CD8, and RNA viral load tests and will be randomly assigned to either saline or mesenchymal stem cell therapy. Investigators will evaluate the safety and efficacy of mesenchymal stem cell therapy based on examination results.
Timeline
- Start
- 2023-04-16
- Primary completion
- 2025-11-15
- Completion
- 2025-11-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | mesenchymal stem cells | Cell therapy | 1e+06 cells/kg | Intravenous |