drugset / Trial / NCT05879744

A Study of CLN-978 in Patients With Relapsed or Refractory (R/R) B Cell Non-Hodgkin Lymphoma (B-NHL)

NCT05879744 ↗

Phase 1 Active not recruiting 90 enrolled Cullinan Therapeutics Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

CLN-978-001 is a Phase 1, open-label, dose escalation and dose expansion study of CLN-978 in patients with Relapse/Refractory (R/R) B-cell Non-Hodgkin Lymphoma (B-NHL).

Timeline

Start
2023-05-31
Primary completion
2026-11
Completion
2027-04

Outcome

Results reported · no primary-endpoint met/missed verdict (typical of a dose-finding / safety study)

release “Clinical observations from three patients treated in a Phase 1 dose escalation trial of patients with B-NHL show that CLN-978 was clinically active.” cullinantherapeutics.com ↗

release “Two of the three patients experienced objective clinical benefit including one patient who experienced a complete response.” cullinantherapeutics.com ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject CLN-978 Other / unclassified — —

Indications