drugset / Trial / NCT05879744
A Study of CLN-978 in Patients With Relapsed or Refractory (R/R) B Cell Non-Hodgkin Lymphoma (B-NHL)
Non-randomizedSequentialOpen-labelTreatment
Summary
CLN-978-001 is a Phase 1, open-label, dose escalation and dose expansion study of CLN-978 in patients with Relapse/Refractory (R/R) B-cell Non-Hodgkin Lymphoma (B-NHL).
Timeline
- Start
- 2023-05-31
- Primary completion
- 2026-11
- Completion
- 2027-04
Outcome
Results reported · no primary-endpoint met/missed verdict (typical of a dose-finding / safety study)
release “Clinical observations from three patients treated in a Phase 1 dose escalation trial of patients with B-NHL show that CLN-978 was clinically active.” cullinantherapeutics.com ↗
release “Two of the three patients experienced objective clinical benefit including one patient who experienced a complete response.” cullinantherapeutics.com ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CLN-978 | Other / unclassified | — | — |