drugset / Trial / NCT05887895
To Compare the Pharmacokinetics and Pharmacodynamics of HR20014, INS068 and INS062 After Single Subcutaneous Injection in Healthy Subjects
RandomizedCrossoverOpen-labelTreatment
Summary
This is a single-center, randomized, open, six-sequence, three-period crossover phase I clinical trial in healthy subjects to compare the PK/PD and safety profiles of single dose of HR20014, INS068, and INS062. In this study, 12 subjects were randomly assigned to 6 administration sequences in a ratio of 1:1:1:1:1:1, and HR20014, INS068 or INS062 injection were given subcutaneously three times before and after each sequence.
Timeline
- Start
- 2023-05-23
- Primary completion
- 2023-07-18
- Completion
- 2023-07-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | HR20014 | Unknown | 0.4 unknown | Subcutaneous |
| Subject | INS062 | Unknown | 0.4 unknown | Subcutaneous |
| Subject | INS068 | Protein / enzyme biologic | 0.4 unknown | Subcutaneous |