drugset / Trial / NCT05887895

To Compare the Pharmacokinetics and Pharmacodynamics of HR20014, INS068 and INS062 After Single Subcutaneous Injection in Healthy Subjects

NCT05887895

Phase 1 Completed 12 enrolled Jiangsu HengRui Medicine Co., Ltd.
RandomizedCrossoverOpen-labelTreatment

Summary

This is a single-center, randomized, open, six-sequence, three-period crossover phase I clinical trial in healthy subjects to compare the PK/PD and safety profiles of single dose of HR20014, INS068, and INS062. In this study, 12 subjects were randomly assigned to 6 administration sequences in a ratio of 1:1:1:1:1:1, and HR20014, INS068 or INS062 injection were given subcutaneously three times before and after each sequence.

Timeline

Start
2023-05-23
Primary completion
2023-07-18
Completion
2023-07-18

Drugs

EvaluationDrugModalityDoseRoute
Subject HR20014 Unknown 0.4 unknown Subcutaneous
Subject INS062 Unknown 0.4 unknown Subcutaneous
Subject INS068 Protein / enzyme biologic 0.4 unknown Subcutaneous

Indications