drugset / Trial / NCT05899608

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients

NCT05899608

Phase 3 Recruiting 1600 enrolled Summit Therapeutics
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a Phase 3 Randomized, double-blind, Multiregional Study of Ivonescimab Combined with Chemotherapy Versus Pembrolizumab Combined with Chemotherapy for the First-line Treatment of Metastatic Non-small Cell Lung Cancer. The primary endpoint is overall survival and progression free survival assessed by investigator. The key secondary endpoints include response and safety.

Timeline

Start
2023-10-26
Primary completion
2028-12-31
Completion
2029-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Ivonescimab Monoclonal antibody Intravenous
Comparator Pembrolizumab Monoclonal antibody Intravenous