drugset / Trial / NCT05899608
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a Phase 3 Randomized, double-blind, Multiregional Study of Ivonescimab Combined with Chemotherapy Versus Pembrolizumab Combined with Chemotherapy for the First-line Treatment of Metastatic Non-small Cell Lung Cancer. The primary endpoint is overall survival and progression free survival assessed by investigator. The key secondary endpoints include response and safety.
Timeline
- Start
- 2023-10-26
- Primary completion
- 2028-12-31
- Completion
- 2029-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ivonescimab | Monoclonal antibody | — | Intravenous |
| Comparator | Pembrolizumab | Monoclonal antibody | — | Intravenous |