drugset / Trial / NCT05900648
Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME)
NaSingle-groupOpen-labelTreatment
Summary
To measure the level of circulating tumor DNA (ctDNA) in the blood of colorectal cancer patients after 6 months of receiving therapy with regorafenib and XmAb20717 (also known as vudalimab). ctDNA is genetic material from tumor cells that can be found and measured in the blood
Timeline
- Start
- 2023-05-17
- Primary completion
- 2024-02-09
- Completion
- 2024-02-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Regorafenib | Small molecule | — | Oral |
| Subject | Vudalimab | Monoclonal antibody | — | Intravenous |