drugset / Trial / NCT05900648

Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME)

NCT05900648

NaSingle-groupOpen-labelTreatment

Summary

To measure the level of circulating tumor DNA (ctDNA) in the blood of colorectal cancer patients after 6 months of receiving therapy with regorafenib and XmAb20717 (also known as vudalimab). ctDNA is genetic material from tumor cells that can be found and measured in the blood

Timeline

Start
2023-05-17
Primary completion
2024-02-09
Completion
2024-02-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Regorafenib Small molecule Oral
Subject Vudalimab Monoclonal antibody Intravenous