drugset

drugset / Trial / NCT05901012

Safety and Tolerability of DMT in Healthy Adults

NCT05901012 ↗

Phase 1 Completed 25 enrolled Federal University of Rio Grande do Norte

RandomizedCrossoverDouble-blindTreatment

Summary

This study aims to evaluate the acute and subacute effects of an inhaled N, N-Dimethyltryptamine (DMT) in healthy individuals.

Timeline

Start: 2023-04-26
Primary completion: 2023-07-17
Completion: 2023-07-17

Publications

Wiessner I, Falchi-Carvalho M, Laborde S, Barros H, Bolcont R, Ruschi Silva S, Pantrigo E, Medina M, Arichelle F, Almeida R, Aires R, Nunes Ferreira LF, Dantas Correa L, Da Costa Bezerra RB, Thie K, Silva-Costa N, de Araujo Costa Neto LA, Jales Lima de Queiroz MV, Galvao-Coelho N, Araujo D, Palhano-Fontes F. Safety, tolerability and subjective effects of vaporized N,N-Dimethyltryptamine: A randomized double-blind clinical trial. Eur Neuropsychopharmacol. 2025 Aug;97:16-27. doi: 10.1016/j.euroneuro.2025.06.002. Epub 2025 Jun 17.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	N,N-Dimethyltryptamine	Unknown	60 mg	Inhaled

Indications

No indication recorded.