drugset / Trial / NCT05905783

Hidradenitis Suppurativa Study of Izokibep

NCT05905783

Phase 3 Terminated 258 enrolled ACELYRIN Inc.
RandomizedParallel-groupDouble-blindTreatment

Summary

Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin 17A, to which it binds with high affinity. This study investigates izokibep in participants with active Hidradenitis Suppurativa (HS), including tumor necrosis factor-alpha inhibitor (TNFi) naïve participants, and those who had an inadequate response or intolerance to TNFi, or for whom TNFi is contraindicated.

Timeline

Start
2023-06-22
Primary completion
2024-07-24
Completion
2025-01-27

Drugs

EvaluationDrugModalityDoseRoute
Subject Izokibep Protein / enzyme biologic Subcutaneous