drugset / Trial / NCT05912387
Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study
NaSingle-groupOpen-labelBasic science
Summary
PSC is a liver disease that has no medical cure. Patients with PSC are at a greatly increased risk of cancer and infection. Additionally, many patients require a liver transplant. Progress towards a cure has been severely limited by an incomplete understanding of why patients develop PSC. The investigators aim to close this gap by conducting a pilot human study in patients with PSC, using statin therapy as a model
Timeline
- Start
- 2023-05-31
- Primary completion
- 2027-05-31
- Completion
- 2027-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rosuvastatin | Small molecule | 20 mg | Oral |