A Study to Investigate Efficacy and Safety With LEO 90100 Compared With Daivobet® Ointment in Adult Chinese Subjects With Stable Plaque Psoriasis

Summary

This study is conducted to assess the efficacy and safety of LEO 90100 when used on the body for the treatment of stable plaque psoriasis in native adult Chinese subjects, compared to Daivobet® ointment.

Timeline

Start

2023-06-21

Primary completion

2024-02-23

Completion

2024-03-05

Publications

• Results Cai L, Zhang F, Zhang G, Lin B, Huang K, Li Y, Wang J, Wan J, Yin W, Zhang G, Ding Y, Meng Z, Xu A, Li L, Zhu X, Zhou Y, Chen R, Duan X, Yu C, Cheng H, Wang L, Yan M, Pan W, Zhu X, Li Z, Han H, Zhang M, Li S, Diao Q, Tao J, Yan W, Xiao R, Zhang J, Yang B, Qiao J, Man X, Wang Z, Qin L, Lyu X, Jorgensen AEM, Kurvits M, Andersen JS, Zhang J. Superior efficacy and comparable safety of calcipotriol plus betamethasone dipropionate foam vs. ointment in Chinese patients with plaque psoriasis: A randomized phase 3 trial. Chin Med J (Engl). 2026 Mar 17. doi: 10.1097/CM9.0000000000003931. Online ahead of print. No abstract available.
• Cai L, Zhang F, Zhang G, Ding Y, Zhou Y, Li S, Tao J, Yan W, Xiao R, Yang B, Qiao J, Man X, Wang Z, El Mongy Jorgensen A, Kurvits M, Andersen JS, Zhang J. Rapid Onset of Action and Quality-of-Life Improvements in Chinese Patients with Plaque Psoriasis Treated with Calcipotriol plus Betamethasone Dipropionate Aerosol Foam in a Randomized Phase 3 Trial. Dermatol Ther (Heidelb). 2026 Jun;16(6):3123-3138. doi: 10.1007/s13555-026-01763-5. Epub 2026 May 3.

Drugs

Indications