drugset / Trial / NCT05920408

Study to Assess EXS21546 in Combination in Patients With Advanced Solid Tumours

NCT05920408 ↗

Phase 1/2 Terminated 6 enrolled Exscientia AI Limited Biotrial Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

A phase 1B/2A study to assess the safety, tolerability, pharmacokinetic and anti-tumoral activity of EXS21546 in combination with a PD-1 inhibitor in patients with advanced solid tumours.

Timeline

Start
2023-04-11
Primary completion
2023-09-27
Completion
2023-10-23

Outcome

Outcome not reported

Stopped: “Emerging data demonstrates challenge for EXS21546 to reach suitable therapeutic index.”

Drugs

EvaluationDrugModalityDoseRoute
Subject EXS21546 Unknown — Oral

Indications