drugset / Trial / NCT05920408
Study to Assess EXS21546 in Combination in Patients With Advanced Solid Tumours
NaSingle-groupOpen-labelTreatment
Summary
A phase 1B/2A study to assess the safety, tolerability, pharmacokinetic and anti-tumoral activity of EXS21546 in combination with a PD-1 inhibitor in patients with advanced solid tumours.
Timeline
- Start
- 2023-04-11
- Primary completion
- 2023-09-27
- Completion
- 2023-10-23
Outcome
Outcome not reported
Stopped: “Emerging data demonstrates challenge for EXS21546 to reach suitable therapeutic index.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | EXS21546 | Unknown | — | Oral |