drugset / Trial / NCT05922150

Effect of LLLT and Ozone to Reduce Complications After Extraction of Impacted Lower Molar

NCT05922150 ↗

Completed 60 enrolled University of Baghdad
RandomizedParallel-groupSingle-blindPrevention

Summary

Many factors cause third molars to stay impacted in the jaws, hence the extraction of impacted wisdom teeth occurs often in dental clinics. Pain, trismus, and edema are typical postoperative complications following third molar surgery. Various strategies have been developed to prevent or reduce these postoperative complications, Among these is the use of Low-Level Laser Therapy (LLLT), which demonstrates numerous benefits in lowering pain, trismus, and edema by managing inflammation. The precise biological mechanism of action remains unknown. There seems to be evidence that it may have neuro-pharmacological impacts on the production, metabolism, and release of a number of biological compounds, the other option is use of ozone which has antimicrobial effectiveness (viricidal, bactericidal, and fungicidal). Additional well-known advantages include immunological modulatory and stimulating actions, including anti-inflammatory, biosynthetic, anti-hypoxic, and bioenergetic characteristics. Ozone can interact with blood components in the right amounts to positively impact oxygen metabolism and cell energy while also triggering antioxidant defense mechanisms

Timeline

Start
2022-03-09
Primary completion
2022-10-01
Completion
2022-11-09

Drugs

EvaluationDrugModalityDoseRoute
Subject ozone gel Unknown — —