drugset / Trial / NCT05924152

A PK Study to Assess the Drug-drug Interaction of a BCRP Inhibitor on Adagrasib

NCT05924152

Phase 1 Completed 16 enrolled Mirati Therapeutics Inc.
Non-randomizedCrossoverOpen-labelOther

Summary

A Phase 1, Open-label, One-sequence Crossover Study to Investigate the Effect of a Breast Cancer Resistance Protein Inhibitor on the Single-dose Pharmacokinetics of Adagrasib in Healthy Adult Subjects

Timeline

Start
2023-06-29
Primary completion
2023-08-09
Completion
2023-08-17

Drugs

EvaluationDrugModalityDoseRoute
Comparator Adagrasib Small molecule 400 mg Oral
Comparator Eltrombopag Small molecule 75 mg Oral

Indications

No indication recorded.