drugset / Trial / NCT05925413

Cadonilimab Plus TACE in Patients With Intermediate-stage Unresectable Hepatocellular Carcinoma

NCT05925413 ↗

Phase 2 Unknown 41 enrolled Eastern Hepatobiliary Surgery Hospital
NaSingle-groupOpen-labelTreatment

Summary

Cadonilimab is a first-in-class bispecific, humanized IgG1 antibody targeting PD-1 and CTLA-4, which has the potential to boost immune surveillance in tumors. The goal of this clinical trial is to evaluated the efficacy and safety of cadonilimab combined with TACE in patients with intermediate-stage unresectable hepatocellular carcinoma.

Timeline

Start
2023-04-24
Primary completion
2024-07-30
Completion
2025-07-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Cadonilimab Monoclonal antibody 15 mg/kg —