drugset / Trial / NCT05926427

Orelabrutinib Combined With Rituximab and Chemotherapy for Relapsed/Refractory B-Cell Lymphoma Patients With Central Nervous System Involvement

NCT05926427

Phase 2 Unknown 25 enrolled Ruijin Hospital
NaSingle-groupOpen-labelTreatment

Summary

This single-center, open, single-arm study aim to evaluate the efficacy and tolerability of a therapy introducing orelabrutinib on the basis of rituximab and chemotherapy in treating patients with relapsed or refractory B-cell lymphoma invloving central nervous system.

Timeline

Start
2023-08-10
Primary completion
2026-04-30
Completion
2026-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Orelabrutinib Small molecule 150 mg Oral
Background Rituximab Monoclonal antibody 375 mg/m2 Intravenous