drugset / Trial / NCT05928962
An Exploratory Single-arm Study: PD-1 With Recombinant Human Adenovirus Type 5 Injection for Malignant Melanomas
NaSingle-groupOpen-labelTreatment
Summary
The goal of this clinical trial is provide new treatment for patients with advanced melanoma who have failed previous immunotherapy. The main questions it aims to answer are: * Efficacy of PD1 monoclonal antibody combined with recombinant human adenovirus type 5 injection in patients with advanced malignant melanoma. * Safety of PD1 monoclonal antibody combined with recombinant human adenovirus type 5 injection in patients with advanced malignant melanoma.
Timeline
- Start
- 2022-10-27
- Primary completion
- 2023-08-01
- Completion
- 2024-10-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Recombinant Human Adenovirus Type 5 Injection | Unknown | 1 ml | Other |
| Subject | Recombinant Human Adenovirus Type 5 Injection | Unknown | 2 ml | Other |
| Subject | Tremelimumab | Monoclonal antibody | 3 mg/kg | Intravenous |