drugset / Trial / NCT05928962

An Exploratory Single-arm Study: PD-1 With Recombinant Human Adenovirus Type 5 Injection for Malignant Melanomas

NCT05928962

Phase 1 Unknown 10 enrolled Fujian Cancer Hospital
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is provide new treatment for patients with advanced melanoma who have failed previous immunotherapy. The main questions it aims to answer are: * Efficacy of PD1 monoclonal antibody combined with recombinant human adenovirus type 5 injection in patients with advanced malignant melanoma. * Safety of PD1 monoclonal antibody combined with recombinant human adenovirus type 5 injection in patients with advanced malignant melanoma.

Timeline

Start
2022-10-27
Primary completion
2023-08-01
Completion
2024-10-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Recombinant Human Adenovirus Type 5 Injection Unknown 1 ml Other
Subject Recombinant Human Adenovirus Type 5 Injection Unknown 2 ml Other
Subject Tremelimumab Monoclonal antibody 3 mg/kg Intravenous

Indications