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drugset / Trial / NCT05930119

HMPL-453 Food Effect and PPI Study in Healthy Volunteer Study

NCT05930119 ↗

Phase 1 Completed 24 enrolled Hutchmed
RandomizedCrossoverOpen-labelTreatment

Summary

A Phase 1, Open-label, 4-Period, Randomized 6-Sequence Study to Evaluate the Effect of Food and Rabeprazole, a Proton Pump Inhibitor, on the Pharmacokinetics of HMPL-453 in Healthy Volunteers

Timeline

Start
2023-03-17
Primary completion
2023-08-28
Completion
2023-08-28

Drugs

EvaluationDrugModalityDoseRoute
Subject HMPL-453 Unknown 300 mg —
Subject Rabeprazole Small molecule 20 mg Oral

Indications

intrahepatic cholangiocarcinoma