drugset / Trial / NCT05931757

A Study of Olverembatinib Combined With Blinatumomab in the Treatment of Ph+ ALL

NCT05931757

Phase 2 Not yet recruiting 22 enrolled The First Affiliated Hospital of Soochow University
NaSingle-groupOpen-labelTreatment

Summary

This is a multicenter, prospective, phase II study for adult de novo Philadelphia chromosome-positive acute lymphoid leukemia (Ph+ ALL) based on the combination of Olverembatinib and Blinatumomab. Olverembatinib will be taken 40mg qod from the time of diagnosis, and Blinatumomab will be given intravenously up to five cycles.

Timeline

Start
2023-07-01
Primary completion
2025-06-30
Completion
2030-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Blinatumomab Monoclonal antibody 28 ug Intravenous
Subject Olverembatinib Small molecule 40 mg Oral