drugset / Trial / NCT05931757
A Study of Olverembatinib Combined With Blinatumomab in the Treatment of Ph+ ALL
NaSingle-groupOpen-labelTreatment
Summary
This is a multicenter, prospective, phase II study for adult de novo Philadelphia chromosome-positive acute lymphoid leukemia (Ph+ ALL) based on the combination of Olverembatinib and Blinatumomab. Olverembatinib will be taken 40mg qod from the time of diagnosis, and Blinatumomab will be given intravenously up to five cycles.
Timeline
- Start
- 2023-07-01
- Primary completion
- 2025-06-30
- Completion
- 2030-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Blinatumomab | Monoclonal antibody | 28 ug | Intravenous |
| Subject | Olverembatinib | Small molecule | 40 mg | Oral |