Comparing Mescaline Sodium Enteric-coated Tablets vs Morte-mescaline in the Treatment of Adult Lupus Nephritis
Summary
The goal of this prospective, multicenter,real-world study is to To evaluate the efficacy and safety of mescaline sodium enteric-coated tablets versus morte-mescaline in the treatment of adult patients with lupus nephritis under real-life medical conditions. The main question it aims to answer are: Is the efficacy of mescaline sodium enteric-coated tablets in the treatment of adult patients with lupus nephritis not inferior to morti-mescaline？ Participants will receive induction and maintenance treatment with mescaline sodium enteric-coated tablets and morte-mescaline.Then participants will be followed up at 60, 180, 270 and 540 days of treatment to assess the efficacy and safety of mescaline sodium enteric-coated tablets compared to morte-mescaline.
Timeline
- Start
- 2023-07-06
- Primary completion
- 2025-07
- Completion
- 2025-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mescaline sodium enteric-coated tablets | Unknown | 360 mg | Oral |
| Subject | Mescaline sodium enteric-coated tablets | Unknown | 540 mg | Oral |
| Comparator | Morte-mescaline | Unknown | 0.5 g | Oral |
| Comparator | Morte-mescaline | Unknown | 0.75 g | Oral |