68Ga-PMD22 PET/CT Examination Targeting CLDN18.2

Summary

To investigate the ability of the CLDN18.2-targeted 68Ga-PMD22 tracer to detect CLDN18.2 expression in patients with gastric and colorectal cancer and other gastrointestinal tumours.

Timeline

Start

2023-05-28

Primary completion

2023-08-31

Completion

2023-08-31

Publications

• Wang R, Bai Z, Zhong W, Li C, Wang J, Xiang J, Du J, Jia B, Zhu Z. Synthesis, preclinical evaluation and pilot clinical translation of [68Ga]Ga-PMD22, a novel nanobody PET probe targeting CLDN18.2 of gastrointestinal cancer. Eur J Nucl Med Mol Imaging. 2024 Oct;51(12):3731-3743. doi: 10.1007/s00259-024-06808-5. Epub 2024 Jun 27.

Drugs

Indications