drugset / Trial / NCT05938907

Effect of Concentrated Growth Factors on Healing of Apicomarginal Defects: a Prospective Study

NCT05938907

Unknown 72 enrolled West China Hospital
RandomizedParallel-groupDouble-blindTreatment

Summary

The persistent and chronic apical periodontitis has caused great difficulties for clinical physicians. Ensuring rapid and successful healing of the extensively damaged periapical region is a pressing issue that needs to be addressed. The treatment options include traditional apical surgery, simultaneous placement of bone powder and membrane after apical surgery, and simultaneous placement of sticky bone (bone powder mixed with concentrated growth factors gel) and membrane. However, high-quality evidence regarding these various treatment options is scarce. The purpose of this study is to compare the advantages and disadvantages of each treatment option, in order to guide clinical physicians in the application of apical surgery.

Timeline

Start
2023-06-15
Primary completion
2024-12
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Concentrated Growth Factor Other / unclassified

Indications

No indication recorded.