The Difference Between Daily and Alternative Day Use of Icodextrin

Summary

Volume overload is an important cause of technical failure in peritoneal dialysis patients. Icodextrin can provide continuous ultrafiltration, which provides a new option for peritoneal dialysis patients. However, icodextrin metabolites are known to accumulate to some extent in the body, resulting in less ultrafiltration with long-term icodextrin use comparing with newly use. Therefore, the investigator hypothesized that a single dose of icodextrin would produce more ultrafiltration volume with the use of icodextrin dialysate on alternate days than with the use of icodextrin dialysate on daily uses.

Timeline

Start

2023-08-01

Primary completion

2023-12-31

Completion

2024-12-28

Drugs

Indications

No indication recorded.