drugset / Trial / NCT05949606

A Study of SI-B001+SI-B003± Chemotherapy in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer

NCT05949606

Phase 1/2 Recruiting 160 enrolled Sichuan Baili Pharmaceutical Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

Phase Ib: To observe the safety and tolerability of the combination of SI-B001 and SI-B003, and to determine the recommended dose of phase II clinical study (RP2D) in the indication of locally advanced or metastatic non-small cell lung cancer. Phase II: To evaluate the efficacy of SI-B001+SI-B003 combination with or without chemotherapy in patients with locally advanced or metastatic non-small cell lung cancer.

Timeline

Start
2023-10-30
Primary completion
2026-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Subject IZALONTAMAB Monoclonal antibody Intravenous
Subject SI-B003 Monoclonal antibody Intravenous