drugset / Trial / NCT05952024

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

NCT05952024

Phase 2 Recruiting 80 enrolled AstraZeneca
NaSingle-groupOpen-labelTreatment

Summary

The study will measure the safety, tolerability, and efficacy with acalabrutinib in combination with rituximab in treatment-naïve elderly and/or frail patients with diffuse large B-cell lymphoma (DLBCL), who are otherwise unsuitable for standard front line chemoimmunotherapy treatments.

Timeline

Start
2024-07-16
Primary completion
2029-04-22
Completion
2029-04-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Acalabrutinib Small molecule Oral
Subject Rituximab Monoclonal antibody Intravenous