drugset / Trial / NCT05953038
LSD Occupancy of the Serotonin 2A Receptor in the Human Brain
NaSingle-groupOpen-labelBasic science
Summary
The investigators wish to quantify the relation between administered dose of lysergic acid diethylamide (LSD), plasma LSD levels, and occupancy at the serotonin 2A receptor (5-HT2AR) using \[11C\]CIMBI-36 positron emission tomography.
Timeline
- Start
- 2023-11-08
- Primary completion
- 2027-12
- Completion
- 2027-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lysergic Acid Diethylamide | Other / unclassified | 25 ug | Oral |
| Subject | Lysergic Acid Diethylamide | Other / unclassified | 50 ug | Oral |
| Subject | Lysergic Acid Diethylamide | Other / unclassified | 75 ug | Oral |
| Subject | Lysergic Acid Diethylamide | Other / unclassified | 100 ug | Oral |
| Subject | Lysergic Acid Diethylamide | Other / unclassified | 125 ug | Oral |
| Subject | Lysergic Acid Diethylamide | Other / unclassified | 150 ug | Oral |
| Subject | Lysergic Acid Diethylamide | Other / unclassified | 175 ug | Oral |
| Subject | Lysergic Acid Diethylamide | Other / unclassified | 200 ug | Oral |
Indications
No indication recorded.