drugset / Trial / NCT05954624
Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid
RandomizedSequentialOpen-labelBasic science
Summary
The drug-drug interaction study had been designed to investigate the effect of ZSP1273 on the pharmacokinetics of digoxin, Rosuvastatin and the effect of Itraconazole and Probenecid on the pharmacokinetics of ZSP1273
Timeline
- Start
- 2023-07-10
- Primary completion
- 2023-11-20
- Completion
- 2023-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Digoxin | Other / unclassified | 0.25 mg | Oral |
| Subject | Itraconazole | Small molecule | 200 mg | Oral |
| Subject | Onradivir | Small molecule | 600 mg | Oral |
| Subject | Probenecid | Small molecule | 500 mg | Oral |
| Subject | Rosuvastatin | Small molecule | 10 mg | Oral |
Indications
No indication recorded.