The Efficacy and Safety of Minocycline in the Treatment of Drug-resistant Epilepsy in NORSE Patients

Summary

Exploring the efficacy and safety of oral minocycline combined with antiepileptic drugs in the treatment of drug-resistant epilepsy in NORSE patients, obtaining preliminary research data, and providing evidence and data support for the next large-scale randomized controlled clinical study.

Timeline

Start

2023-03-01

Primary completion

2024-03-01

Completion

2025-03-01

Publications

• Feng L, Li H, Ma L, Hu M, Hui B, Sun Z, Wang X, Wang Y, Jiang W. Minocycline in chronic management of febrile infection-related epilepsy syndrome (FIRES): a case series and literature review of treatment strategies. Acta Epileptol. 2025 Jun 6;7(1):35. doi: 10.1186/s42494-025-00224-4.

Drugs

Indications