drugset / Trial / NCT05959096

A Study of LY3437943 in Healthy Participants With a High Body Mass Index

NCT05959096

Phase 1 Completed 85 enrolled Eli Lilly and Company
RandomizedParallel-groupOpen-labelBasic science

Summary

The study is conducted in two parts (Part A and B). The main purpose of this study is to look at the amount of the LY3437943 that gets into the blood stream and how long it takes the body to get rid of it when given subcutaneously (SC, under the skin) in the upper arm and thigh compared to the abdomen in healthy participants with high body mass index (BMI) in Part A. In Part B, the participants receive LY3437943 intravenously (IV, through a vein) where the safety and tolerability of LY3437943 are evaluated and information about any side effects experienced will be collected. For each participant, the total duration of the study will be approximately up to 157 days and 99 days for Part A and Part B, respectively.

Timeline

Start
2023-07-18
Primary completion
2024-07-25
Completion
2024-07-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Retatrutide Protein / enzyme biologic Subcutaneous

Indications

No indication recorded.