Intra-wound Vancomycin Powder for Prevention of Surgical Site Infection Following Spinal Surgery

Summary

Cefazolin is given routinely pre and intraoperatively for patients undergoing spinal surgery to reduce the rate of infection. Intra-wound admission of Vancomycin powder has been suggested to reduce wound infection rates. Therefore, this study aims to compare the rate of wound-related complications between patients receiving standard treatment compared to patients receiving an addition of topical Vancomycin and to identify the optimal Vancomycin dosage. All groups will receive the recommended regimen of routine IV antibiotic prophylaxis.

Timeline

Start

2020-05-31

Primary completion

2025-12-01

Completion

2026-12-01

Drugs

Indications