drugset / Trial / NCT05962151

Refractory Chronic Cough Improvement Via NAL ER (RIVER)

NCT05962151

Phase 2 Completed 66 enrolled Trevi Therapeutics
RandomizedCrossoverDouble-blindTreatment

Summary

The main purpose of this study is to evaluate the effect of NAL ER on 24-hour cough frequency and to assess safety and tolerability of NAL-ER for treatment of refractory chronic cough.

Timeline

Start
2023-11-30
Primary completion
2025-01-06
Completion
2025-01-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Nalbuphine Small molecule 27 mg Oral
Subject Nalbuphine Small molecule 54 mg Oral
Subject Nalbuphine Small molecule 108 mg Oral