drugset / Trial / NCT05965193
Normobaric Hyperoxia Combined With Intravenous Thrombolysis for Acute Ischemic Stroke：Longterm Outcome (OPENS-3L)
Phase 3
Unknown
1230 enrolled
Ji Xunming,MD,PhD
Affiliated Hospital of Nantong University · collabBeijing Friendship Hospital · collabBeijing Shijitan Hospital, Capital Medical University · collabBeijing Tongren Hospital · collabChangsha Central Hospital · collabGuizhou Provincial People's Hospital · collabJining First People's Hospital · collabLinyi People's Hospital · collabNanyang Central Hospital · collabPeople's Hospital of Beijing Daxing District · collabRizhao People's Hospital · collabSecond Affiliated Hospital of Nanchang University · collabShandong Provincial Hospital · collabThe Affiliated Hospital of Xuzhou Medical University · collabThe First Affiliated Hospital of Soochow University · collabThe First Affiliated Hospital of Zhengzhou University · collabThe Second Hospital of Anhui Medical University · collabTianjin Huanhu Hospital · collabZhumadian Central Hospital · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to determine the long-term efficacy and safety of Normobaric Hyperoxia combined with intravenous thrombolysis for acute ischemic stroke.
Timeline
- Start
- 2023-08-17
- Primary completion
- 2025-08-30
- Completion
- 2025-10-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Alteplase | Protein / enzyme biologic | 0.9 mg/kg | Intravenous |