drugset / Trial / NCT05966935
Effect of Fenugreek and Cumin Powder on Overweight and Obese People
RandomizedParallel-groupOpen-labelTreatment
Summary
The objective of this study is to investigate the effect of fenugreek and cumin powder on the anthropometric indices of overweight and obese adults aged 18-30 years. This study design intends to answer following question: Will fenugreek and cumin powder mixture result in change of anthropometric measurements {Body Mass Index\[BMI\], Waist-Hip Ratio, Fat Mass
Timeline
- Start
- 2023-09-15
- Primary completion
- 2023-11-20
- Completion
- 2023-12-28
Publications
- Background Khosla P, Gupta DD, Nagpal RK. Effect of Trigonella foenum graecum (Fenugreek) on blood glucose in normal and diabetic rats. Indian J Physiol Pharmacol. 1995 Apr;39(2):173-4.
- Background Geberemeskel GA, Debebe YG, Nguse NA. Antidiabetic Effect of Fenugreek Seed Powder Solution (Trigonella foenum-graecum L.) on Hyperlipidemia in Diabetic Patients. J Diabetes Res. 2019 Sep 5;2019:8507453. doi: 10.1155/2019/8507453. eCollection 2019.
- Background Hameed S, Arshad MS, Ahmad RS, Hussain G, Imran M, Arshad MU, Ahmed A, Imran M, Imran A. Potential preventive and protective perspectives of different spice powders and their mixtures in rat model. Lipids Health Dis. 2020 Apr 23;19(1):78. doi: 10.1186/s12944-020-01223-9.
- Background Khateeb S, Albalawi A, Alkhedaide A. Regulatory effect of diosgenin on lipogenic genes expression in high-fat diet-induced obesity in mice. Saudi J Biol Sci. 2021 Jan;28(1):1026-1032. doi: 10.1016/j.sjbs.2020.11.045. Epub 2020 Nov 18.
- Background Kumar P, Bhandari U, Jamadagni S. Fenugreek seed extract inhibit fat accumulation and ameliorates dyslipidemia in high fat diet-induced obese rats. Biomed Res Int. 2014;2014:606021. doi: 10.1155/2014/606021. Epub 2014 Apr 29.
- Background Laudadio V, Nasiri-Dehbaneh M, Bilal RM, Qotbi A, Javandel F, Ebrahimi A, Seidavi A, Slozhenkina M, Gorlov I, Dunne PG, Tufarelli V. Effects of different levels of dietary black cumin (Nigella sativa L.) and fenugreek (Trigonella foenum-graecum L.) and their combination on productive traits, selected blood constituents, microbiota and immunity of broilers. Anim Biotechnol. 2022 Oct;33(5):941-954. doi: 10.1080/10495398.2020.1853138. Epub 2020 Dec 16.
- Background Mathern JR, Raatz SK, Thomas W, Slavin JL. Effect of fenugreek fiber on satiety, blood glucose and insulin response and energy intake in obese subjects. Phytother Res. 2009 Nov;23(11):1543-8. doi: 10.1002/ptr.2795.
- Background Tavakoli-Rouzbehani OM, Faghfouri AH, Anbari M, Nikpayam O, PourMirzaei Olyaei H, Alizadeh M. Efficacy of Cuminum Cyminum supplementation on lipid profile and anthropometric parameters: A systematic review and meta-analysis of randomized controlled clinical trials. Phytother Res. 2022 Jan;36(1):380-394. doi: 10.1002/ptr.7327. Epub 2021 Nov 25.
- Background Peng Y, Sun Q, Xu W, He Y, Jin W, Yuan L, Gao R. Vitexin ameliorates high fat diet-induced obesity in male C57BL/6J mice via the AMPKalpha-mediated pathway. Food Funct. 2019 Apr 1;10(4):1940-1947. doi: 10.1039/c9fo00148d. Epub 2019 Mar 15.
- Background Said O, Saad B, Fulder S, Khalil K, Kassis E. Weight loss in animals and humans treated with "weighlevel", a combination of four medicinal plants used in traditional arabic and islamic medicine. Evid Based Complement Alternat Med. 2011;2011:874538. doi: 10.1093/ecam/nen067. Epub 2011 Jun 16.
- Background Sharma MS, Choudhary PR. Effect of Fenugreek Seeds Powder (Trigonella foenum-graecum L.) on Experimental Induced Hyperlipidemia in Rabbits. J Diet Suppl. 2017 Jan 2;14(1):1-8. doi: 10.3109/19390211.2016.1168905. Epub 2016 Apr 12.
- Background Yadav UC, Baquer NZ. Pharmacological effects of Trigonella foenum-graecum L. in health and disease. Pharm Biol. 2014 Feb;52(2):243-54. doi: 10.3109/13880209.2013.826247. Epub 2013 Oct 9.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cumin | Traditional medicine (herbal / TCM) | 5 g | — |
| Subject | Fenugreek | Traditional medicine (herbal / TCM) | 5 g | — |
Indications
No indication recorded.