drugset / Trial / NCT05974241

Irritability in Children With ADHD and Emotion Dysregulation

NCT05974241

Phase 4 Completed 36 enrolled Tri-Service General Hospital (TSGH)
NaSequentialOpen-labelTreatment

Summary

Objective: Emotion dysregulation is common among children with ADHD and associated with a broad range of adult psychopathology, which is similar to the longitudinal outcomes of childhood irritability. However, the profiles of irritability in children with ADHD and emotion dysregulation has been understudied. This study aimed to investigate the efficacy of methylphenidate and aripiprazole in the treatment of irritability in children with ADHD and emotion dysregulation. In addition, the clinical profiles and neuropsychological characteristics of irritability in children with ADHD were explored.

Timeline

Start
2017-04-21
Primary completion
2022-04-07
Completion
2022-04-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Aripiprazole Other / unclassified
Subject Methylphenidate Small molecule