drugset / Trial / NCT05977647
Medical Stone Expulsive Therapy for Acutely Obstructed Ureteric Calculi
RandomizedParallel-groupOpen-labelTreatment
Summary
As a first treatment option for small-size ureteric stones, α-blockers are now being used for medical expulsive therapy (MET) instead of invasive procedures. There is high evidence of the therapeutic benefit of α-blockers in the treatment of Distal ureteric stone (DUS); also endorsed by international guidelines. However, limited data is available worldwide, on the effect of silodosin to treat DUS. A multi-center study is needed to confirm the efficacy and safety of therapy.
Timeline
- Start
- 2024-09-01
- Primary completion
- 2025-05-30
- Completion
- 2025-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Silodosin | Unknown | 8 mg | Oral |
| Comparator | Tamsulosin | Other / unclassified | 0.4 mg | Oral |